Radiation induced depigmentation disorder in two patients with breast cancer: Exploring a rare accompaniment

Abstract

Radiation induced depigmentation disorder is a rare accompaniment. We herein report two patients of bilateral breast cancer developing depigmentation disorder, initially confined to the radiation portal with subsequent generalization within few months of completion of whole breast radiotherapy. Both these patients had no prior history of vitiligo or other autoimmune disorder. This brief report highlights the importance of awareness of this association in appropriate decision making in susceptible patients thereby preventing this morbidity and its psychological ramifications.

Keywords

• Radiation
• De-pigmentation
• Vitiligo