Anatomical Sciences Journal (May 2013)

Relationship between Sperm Parameters and DNA Fragmentation using a Halosperm Kit

  • Houshang Rafighdoost,
  • Mir Mehrdad Farsi,
  • Maryam Javadi,
  • Soraya Khafri

Journal volume & issue
Vol. 10, no. 2
pp. 79 – 86

Abstract

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Introduction: tegrity is the most important component for transferring genetic information Sperm DNA fragmentation is considered a component of male infertility. Its assessment comprises conventional semen analysis of which emphasis is placed on its evaluation in fertility clinics. In this study, we investigate the relationship between sperm parameters of motility, morphology, concentration, and DNA fragmentation level (DFLs) in sperm. Materials and Methods: 89: nfertile men were assessed by conventional sperm analysis. DFLs were determined by Halosperm, a sperm chromatin dispersion test (SCD) which was performed in both groups of patients, the low DNA fragmentation group (LFG≤30%) and high DNA fragmentation group (HFG) 30%. Results: Sperm parameters of concentration (p30% in the percent of men with normal semen parameters, the high importance of performing a DF test in the clinic setting in order to determine sperm DNA problems and the presence of sperm abnormalities in patients is recommended.

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