487 NC410, a fusion protein of LAIR-2 (Leukocyte Associated Immunoglobulin-like Receptor) with human IgG1 Fc, is safe & tolerable with evidence of immune modulation in subjects with advanced solid tumors

• Ravi Madan,
• Siqing Fu,
• Marijo Bilusic,
• John Shin,
• Martin Gutierrez,
• Linjie Tian,
• Dallas Flies,
• Linda Liu,
• Solomon Langermann,
• Han Myint,
• Jahangheer Shaik,
• Emilia Barbu,
• Qinjie Zhou,
• Aaron Morawski,
• Hasan Abukharma,
• Ron Copeland,
• Megan Nelson,
• Stephanie Zeidan,
• Danielle Pastor

Affiliations

Ravi Madan

Aff2 grid.48336.3a0000000419368075National Cancer Institute Bethesda MD USA

Siqing Fu

2 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Marijo Bilusic

Genitourinary Malignancy Branch, National Cancer Institute, Bethesda, Maryland, USA

John Shin

2 Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts, USA

Martin Gutierrez

Hackensack University Medical Center, Hackensack, New Jersey, USA

Linjie Tian

2NextCure, Beltsville, MD, USA

Dallas Flies

2NextCure, Beltsville, MD, USA

Linda Liu

2NextCure, Beltsville, MD, USA

Solomon Langermann

2NextCure, Beltsville, MD, USA

Han Myint

1NextCure LLC, Beltsville, MD, USA

Jahangheer Shaik

1NextCure LLC, Beltsville, MD, USA

Emilia Barbu

1NextCure LLC, Beltsville, MD, USA

Qinjie Zhou

1NextCure LLC, Beltsville, MD, USA

Aaron Morawski

1NextCure LLC, Beltsville, MD, USA

Hasan Abukharma

1NextCure LLC, Beltsville, MD, USA

Ron Copeland

1NextCure LLC, Beltsville, MD, USA

Megan Nelson

1NextCure LLC, Beltsville, MD, USA

Stephanie Zeidan

1NextCure LLC, Beltsville, MD, USA

Danielle Pastor

2National Cancer Institute, Bethesda, MD, USA