Microbial Biotechnology (Feb 2024)

A perspective current and past modes of inhalation therapy

  • José Canto Mangana,
  • Kelsey Aguirre Schilder,
  • José Ignacio Bretones‐Pedrinaci,
  • Ana Rosa Márquez Blesa,
  • Fermín Sánchez deMedina,
  • Olga Martínez‐Augustin,
  • Abdelali Daddaoua

DOI
https://doi.org/10.1111/1751-7915.14419
Journal volume & issue
Vol. 17, no. 2
pp. n/a – n/a

Abstract

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Abstract Inhalation is the preferred route of delivery for anti‐asthma and chronic obstructive pulmonary disease (COPD) drugs. The use of this route has demonstrated efficacy in these and other conditions, it offers rapid onset of action, and is associated with minimal systemic exposure, thereby reducing the risk of adverse effects. Therefore, the current brief covers an interesting collection of inhaler action modes, shedding light on their molecular mechanisms and clinical applications for anti‐asthma, COPD and antibacterial inhalation therapy. Hence, not only enriches our understanding of inhalation therapy molecular intricacies but also provides a comprehensive overview of the evolving landscape in clinical and antibacterial inhalation therapy. In doing so, it underscores the pivotal role of microbiology and biotechnology in advancing therapeutic approaches that harness the power of inhalation.