Implication of TIGIT+ human memory B cells in immune regulation

Md Mahmudul Hasan; Sumi Sukumaran Nair; Jacqueline G. O’Leary; LuAnn Thompson-Snipes; Verah Nyarige; Junwen Wang; Walter Park; Mark Stegall; Raymond Heilman; Goran B. Klintmalm; HyeMee Joo; SangKon Oh

doi:10.1038/s41467-021-21413-y

Nature Communications (Mar 2021)

Implication of TIGIT+ human memory B cells in immune regulation

Md Mahmudul Hasan,
Sumi Sukumaran Nair,
Jacqueline G. O’Leary,
LuAnn Thompson-Snipes,
Verah Nyarige,
Junwen Wang,
Walter Park,
Mark Stegall,
Raymond Heilman,
Goran B. Klintmalm,
HyeMee Joo,
SangKon Oh

Affiliations

Md Mahmudul Hasan: Department of Immunology, Mayo Clinic
Sumi Sukumaran Nair: Department of Medicine, Mayo Clinic
Jacqueline G. O’Leary: Baylor University Medical Center
LuAnn Thompson-Snipes: Baylor University Medical Center
Verah Nyarige: Department of Health Sciences Research, Mayo Clinic
Junwen Wang: Department of Health Sciences Research, Mayo Clinic
Walter Park: William J. von Liebig Transplant Center, Mayo Clinic
Mark Stegall: William J. von Liebig Transplant Center, Mayo Clinic
Raymond Heilman: Department of Medicine, Mayo Clinic
Goran B. Klintmalm: Baylor University Medical Center
HyeMee Joo: Department of Immunology, Mayo Clinic
SangKon Oh: Department of Immunology, Mayo Clinic

DOI: https://doi.org/10.1038/s41467-021-21413-y
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 15

Abstract

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Regulatory B cells have been shown to play critical roles in the modulation of the immune system. Here, the authors implicate TIGIT expression in B cells with the process of immuno-regulation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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