Inflammation and Regeneration (Dec 2022)

Neutralizing and enhancing antibodies against SARS-CoV-2

  • Yafei Liu,
  • Hisashi Arase

DOI
https://doi.org/10.1186/s41232-022-00233-7
Journal volume & issue
Vol. 42, no. 1
pp. 1 – 9

Abstract

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Abstract The high transmissibility and rapid global spread of SARS-CoV-2 since 2019 has led to a huge burden on healthcare worldwide. Anti-SARS-CoV-2 neutralizing antibodies play an important role in not only protecting against infection but also in clearing the virus and are essential to providing long-term immunity. On the other hand, antibodies against the virus are not always protective. With the emergence of SARS-CoV-2 immune escape variants, vaccine design strategies as well as antibody-mediated therapeutic approaches have become more important. We review some of the findings on SARS-CoV-2 antibodies, focusing on both basic research and clinical applications.

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