Nature Communications (Mar 2023)
Mucociliary Wnt signaling promotes cilia biogenesis and beating
Abstract
Motile cilia are thought of as signaling-inert nanomotors. Here, the authors show that motile cilia transduce a Wnt-protein phosphatase 1 signal that regulates cilia biogenesis and ciliary beating in Xenopus embryos and in human airway epithelia.