mBio
(Feb 2021)
Sirtuin 3 Downregulation in
<i>Mycobacterium tuberculosis</i>
-Infected Macrophages Reprograms Mitochondrial Metabolism and Promotes Cell Death
- Lorissa J. Smulan,
- Nuria Martinez,
- Michael C. Kiritsy,
- Chido Kativhu,
- Kelly Cavallo,
- Christopher M. Sassetti,
- Amit Singhal,
- Heinz G. Remold,
- Hardy Kornfeld
Affiliations
- Lorissa J. Smulan
- Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- Nuria Martinez
- Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- Michael C. Kiritsy
- Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- Chido Kativhu
- Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- Kelly Cavallo
- Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- Christopher M. Sassetti
- Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- Amit Singhal
- Infectious Disease Horizontal Technology Centre, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore
- Heinz G. Remold
- Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
- Hardy Kornfeld
- ORCiD
- Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- DOI
-
https://doi.org/10.1128/mBio.03140-20
- Journal volume & issue
-
Vol. 12,
no. 1
Abstract
Read online
Tuberculosis, the disease caused by the bacterium M. tuberculosisM. tuberculosisM. tuberculosisM. tuberculosis
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