Evaluation of antibacterial and phytochemical analysis of root extracts of Alysicarpus vaginalis DC. Against Respiratory Tract Pathogens

Abstract

The present study was to evaluate the antibacterial activity and phytochemical analysis of various roots extracts of Alysicarpus vaginalis (Chukalai) against selected common respiratory tract pathogens i.e. Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Klebsiella pneumonia and Pseudomonas aeruginosa. Results showed that methanol extract was more efficient in comparison to other extracts. The zone of inmibition ranged between 10 ± 0.57 to 13 ± 0.32 mm examined at 200 mg/ml, respectively. Minimum inhibitory concentration was recorded for MeOH extracts between 3.12 mg/ml to 25 mg/ml for all the pathogens. The Phytochemical analysis of extracts showed the presence of flavonoids, glycosides, alkaloids, steroids, terpenes, saponins and tannins. This investigation supports a good response to the use of A.vaginalis in herbal medicine and as a base for the development of new drugs and phytomedicine in foundation for its use in treatment of respiratory infectious diseases.

Keywords

• Alysicarpus vaginalis
• antibacterial activity
• minimum inhibitory concentration
• respiratory tract pathogens