Efficacy of 4-hour rescue therapeutic plasma exchange in severe septic shock patients

Abstract

Background.Early intervention for septic shock is crucial to reduce mortality and improve outcome. There is still a great debate over the exact time of therapeutic plasma exchange (TPE) administration in septic shock patients. This study aims to investigate the effect of early initiation (within 4 hours) of TPE in severe septic shock on hemodynamics & outcome.

Keywords

• septic shock
• plasma exchange
• hemodynamics
• norepinephrine
• critical care