Progress of nanopreparation technology applied to volatile oil drug delivery systems
Zu-Wen Ye,
Qi-Yue Yang,
Qiao-Hong Lin,
Xiao-Xia Liu,
Feng-Qin Li,
Hong-Da Xuan,
Ying-Yan Bai,
Ya-Peng Huang,
Le Wang,
Fang Wang
Affiliations
Zu-Wen Ye
Cancer Research Centre, Jiangxi University of Chinese Medicine, 330004, China
Qi-Yue Yang
Affiliated Hospital of Chengdu University of Chinese Medicine, 610072, China
Qiao-Hong Lin
Cancer Research Centre, Jiangxi University of Chinese Medicine, 330004, China
Xiao-Xia Liu
Cancer Research Centre, Jiangxi University of Chinese Medicine, 330004, China
Feng-Qin Li
Cancer Research Centre, Jiangxi University of Chinese Medicine, 330004, China
Hong-Da Xuan
Cancer Research Centre, Jiangxi University of Chinese Medicine, 330004, China
Ying-Yan Bai
Cancer Research Centre, Jiangxi University of Chinese Medicine, 330004, China
Ya-Peng Huang
Cancer Research Centre, Jiangxi University of Chinese Medicine, 330004, China
Le Wang
Cancer Research Centre, Jiangxi University of Chinese Medicine, 330004, China; Corresponding author. Cancer Research Centre, Jiangxi University of Chinese Medicine, No. 1688 Mei Lin Avenue, 330004 Nanchang, China.
Fang Wang
Cancer Research Centre, Jiangxi University of Chinese Medicine, 330004, China; Corresponding author. Cancer Research Centre, Jiangxi University of Chinese Medicine, No. 1688 Mei Lin Avenue, 330004 Nanchang, China.
Traditional Chinese medicine volatile oil has a long history and possesses extensive pharmacological activity. However, volatile oils have characteristics such as strong volatility, poor water solubility, low bioavailability, and poor targeting, which limit their application. The use of volatile oil nano drug delivery systems can effectively improve the drawbacks of volatile oils, enhance their bioavailability and chemical stability, and reduce their volatility and toxicity. This article first introduces the limitations of the components of traditional Chinese medicine volatile oils, discusses the main classifications and latest developments of volatile oil nano formulations, and briefly describes the preparation methods of traditional Chinese medicine volatile oil nano formulations. Secondly, the limitations of nano formulation technology are discussed, along with future challenges and prospects. A deeper understanding of the role of nanotechnology in traditional Chinese medicine volatile oils will contribute to the modernization of volatile oils and broaden their application value.
