HEMOLYTIC ANEMIA IMUNNE-MEDIATED IN DOGS

Scientific Electronic Archives. 2016;9(5):72-84

 

Journal Homepage

Journal Title: Scientific Electronic Archives

ISSN: 2316-9281 (Print)

Publisher: Universidade Federal de Mato Grosso

Society/Institution: UFMT

LCC Subject Category: General Works

Country of publisher: Brazil

Language of fulltext: Portuguese, English

Full-text formats available: PDF

 

AUTHORS

R. C. Castilho
M. O. Lima
M. F. R. Cruz
E. S. Marquez
C. Calderón

EDITORIAL INFORMATION

Peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 15 weeks

 

Abstract | Full Text

Due to the reduction in the number of red blood cells, caused by the immune system, the immune-mediated hemolytic anemia (IMHA) is the most common disease among the hemolytic anemias and occurs more frequently in dogs (Nelson & Couto, 2010), wherein the most affected breeds are Cocker Spaniel, Poodle, Doberman and Collie (ETTINGER; FELDMAN 2004; THRALL et al 2007.). There is no pathognomonic sign for the diagnosis of the immune-mediated hemolytic anemia; however, laboratory findings show regenerative anemia, spherocytosis, positive results in Coombs' test and rarely, monocytes with hemosiderin or erythrocytes phagocytosis, but even with these findings, the primary and secondary IMHA can not be differentiate from each other. Differentiation can only be achieved when there is a deep investigation into the cause of the anemia. The IMHA therapeutics starts with the support treatment and follows with an immunosuppressive therapy. In relation to IMHA Mortality rates, the numbers range from 25% to 50% (Thrall, 2007), or above 70% (CARR; Panciera; Kidd, 2002).