Revista Alergia México (2019-06-01)

GUIMIT 2019, Mexican Guideline on Immunotherapy. Guideline on the diagnosis of IgE-mediated allergic disease and immunotherapy following the ADAPTE approach

  • Désirée Larenas-Linnemann,
  • Jorge A. Luna-Pech,
  • Noel Rodríguez-Pérez,
  • Mónica Rodríguez-González,
  • Alfredo Arias-Cruz,
  • María Virginia Blandón-Vijil,
  • María del Carmen Costa-Domínguez,
  • Blanca E. Del Río-Navarro,
  • Alan Estrada-Cardona,
  • Elsy Maureen Navarrete-Rodríguez,
  • José Antonio Ortega-Martell,
  • César Fireth Pozo-Beltrán,
  • Herson Brito-Díaz,
  • María del Rosario Canseco-Raymundo,
  • Enrique Emanuel Castelán-Chávez,
  • Margarita Gabriela Domínguez-Silva,
  • Alberto José Escalante-Domínguez,
  • José Luis Gálvez-Romero,
  • María Guadalupe García-Reyes,
  • Javier Gómez-Vera,
  • Sandra Nora González-Díaz,
  • María Gracias Belinda Guerrero-Núñez,
  • Dante Hernández-Colín,
  • Alejandra Macías-Weinmann,
  • David Alejandro Mendoza-Hernández,
  • Néstor Alejandro Meneses-Sánchez,
  • María Dolores Mogica-Martínez,
  • Carol Vivian Moncayo-Coello,
  • Manuel Montiel-Herrera,
  • Patricia O’Farril-Romanillos,
  • Ernesto Onuma-Takane,
  • Margarita Ortega-Cisneros,
  • Lorena Rangel-Garza,
  • Héctor Stone-Aguilar,
  • Carlos Torres-Lozano,
  • Edna Venegas-Montoya,
  • Guillermo Wakida-Kusunoki,
  • Carlos Macouzet-Sánchez,
  • Armando Partida-Gaytán,
  • Aída Inés López-García,
  • Ana Paola Macías-Robles,
  • María de Jesús Ambriz-Moreno,
  • Amyra Ali Azamar-Jácome,
  • Carlos Báez-Loyola,
  • Claudia Yusdivia Beltrán-De Paz,
  • Chrystopherson Caballero-López,
  • Juan Carlos Fernández de Córdova-Aguirre,
  • Roberto Fernández-Soto,
  • José Santos Lozano-Sáenz,
  • José Joel Oyoqui-Flores,
  • Roberto Osorio-Escamilla,
  • Fernando Ramírez,
  • Daniela Rivero-Yeverino,
  • María del Socorro Orozco-Martínez,
  • María Isabel Rojo-Gutiérrez,
  • Eric Martínez,
  • Miguel Alejandro Medina-Ávalos

DOI
https://doi.org/10.29262/ram.v66i5.631
Journal volume & issue
Vol. 66 suppl 1
pp. 1 – 105

Abstract

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Background: In Mexico, allergen immunotherapy (AIT) and immunotherapy with hymenoptera venom (VIT) is traditionally practiced combining aspects of the European and American school. In addition, both types of extracts (European and American) are commercially available in Mexico. Moreover, for an adequate AIT/VIT a timely diagnosis is crucial. Therefore, there is a need for a widely accepted, up-to-date national immunotherapy guideline that covers diagnostic issues, indications, dosage, mechanisms, adverse effects and future expectations of AIT (GUIMIT 2019). Method: With nationwide groups of allergists participating, including delegates from postgraduate training-programs in Allergy/Immunology-forming, the guideline document was developed according to the ADAPTE methodology: the immunotherapy guidelines from European Academy of Allergy and Clinical Immunology, German Society for Allergology and Clinical Immunology, The American Academy of Allergy, Asthma and Immunology and American College of Allergy, Asthma, and Immunology were selected as mother guidelines, as they received the highest AGREE-II score among international guidelines available; their evidence conforms the scientific basis for this document. Results: GUIMIT emanates strong or weak (suggestions) recommendations about practical issues directly related to in vivo or in vitro diagnosis of IgE mediated allergic diseases and the preparation and application of AIT/VIT and its adverse effects. GUIMIT finishes with a perspective on AIT modalities for the future. All the statements were discussed and voted on until > 80 % consensus was reached. Conclusion: A wide and diverse group of AIT/VIT experts issued transculturized, evidence-based recommendations and reached consensus that might improve and standardize AIT practice in Mexico.

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