Study of cases of pregnancy with jaundice in a tertiary care teaching hospital in Western India

Abstract

Objective: This study was undertaken to evaluate incidence, etiological factors and fetomaternal outcome in pregnancy with jaundice in a tertiary care teaching hospital. Methods: Antenatal patients with jaundice admitted to Civil hospital, Ahmedabad between January 2018 to January 2020 were included in the study. Results: Incidence of jaundice in pregnancy was found to be 0.65% in present study. Most common cause of jaundice was viral hepatitis. Most commonly involved patients belonged to age group 25 - 29 years, primigravida belonging to lower socioeconomic class presenting with yellowish discolouration of sclera and/or urine as most common presenting symptom with altered liver enzyme levels. DIC, PPH were amongst the most common factors causing morbidity. Neonatal hyperbilirubinemia, perinatal mortality, meconium stained liquor, fetal distress were main causes involved in perinatal outcome and morbidity. The maternal mortality rate was 21% and perinatal mortality rate was 23 %. Conclusion: Jaundice in pregnancy has adverse fetomaternal outcome. Improvement in health awareness, education & routine and regular antenatal check-up, early referrals can result in early diagnosis and treatment of jaundice in pregnancy thus reducing the fetal and maternal morbidity and mortality.

Keywords

• jaundice
• fetomaternal outcome
• pregnancy