Analysis of the Clinicopathological Features of Hepatocellular Carcinoma in Elderly Patients

Abstract

The peak age of onset of hepatocellular carcinoma (HCC) is continually increasing worlwide. This study aims to evaluate whether there exists any significant difference in the clinicopathological features between younger- and elderly-HCC.1082 Consecutive patients with HCC who underwent liver resection at Liver Cancer Institute, Zhongshan Hospital, Fudan University from 1995 to 1998 were studied. The patients were divided into elderly-HCC (>/=65 years of age) and younger-HCC (/=400mug/dl; (4) a relatively small tumor diameter; (5) higher proportion of stage I-II patients; (6) a relatively low metastasis rate. However, there were no statistically significant differences in other clinicopathological features (including gender, symptoms, tumor number, tumor venous invasion, tumor differentiation, capsular formation, type of cirrhosis) between the two groups. There is a certain extent difference in clinicopathological features between elderly and younger-HCC patients, but the postoperative survival rate is comparable between the two groups. JNMA J Nepal Med Assoc. 2008 Jul-Sep;47(171):132-135.