Indian Journal of Ophthalmology (Jan 2012)
Quantification of retinal nerve fiber layer thickness using spectral domain optical coherence tomography in normal Indian population
- Tarannum Mansoori,
- Kalluri Viswanath,
- Nagalla Balakrishna
Affiliations
- Tarannum Mansoori
- Kalluri Viswanath
- Nagalla Balakrishna
- DOI
- https://doi.org/10.4103/0301-4738.103797
- Journal volume & issue
-
Vol. 60,
no. 6
pp. 555 – 558
Abstract
The purpose of this study was to measure peripapillary retinal nerve fiber layer thickness (RNFLT) using spectral domain optical coherence tomography (SD-OCT) in normal Indian eyes, for which, 210 normal volunteers were recruited. One eye of each subject underwent RNFL scanning at 3.4 mm circle diameter around optic nerve using SD OCT. The data were analyzed to determine RNFLT in the sample population and its variation with age and gender. The average peripapillary RNFLT was 114.03 ± 9.59 μm. There was no effect of gender on RNFLT parameters. Age had significant negative correlation with average (P = 0.005), superior (P = 0.04), temporal (P = 0.049), and nasal quadrants (P = 0.01) RNFLT. Inferior quadrant RNFLT also had a negative correlation with age, but it was not statistically significant (P = 0.15).
Keywords
- Accommodation
- disaccommodation
- mydriasis
- phenylephrine hydrochloride
- pupil
- velocity
- Growth
- human adult
- lens diameter
- lens dry weight
- lens thickness
- lens wet weight
- Silicone oil removal
- encirclage
- 360 retinopexy
- oil emulsification
- silicone oil tamponade
- Age-related macular degeneration
- chorodial neovascularization
- ocular trauma
- polypoidal choroidal vasculopathy
- retinal macroaneurysm
- submacular hemorrhage
- subretinal hemorrhage
- tissue plasminogen activator
- vitrectomy
- Insulin-like growth factor-1
- insulin-like growth factor binding protein-3
- retinopathy of prematurity
- Brilliant Blue G
- dextrose normal saline 10%
- internal limiting membrane
- macular hole
- Angle closure
- anterior chamber angle
- blotchy pigments
- glaucomatous optic neuropathy
- peripheral anterior synechiae
- Cardiff acuity cards
- lea grating
- visual acuity in pre-verbal children
- Contrast sensitivity
- contrast visual acuity
- retinitis pigmentosa
- Bevacizumab
- choroidal neovacular membrane
- panuveitis
- triamcinolone acetonide
- Vogt-Koyanagi-Harada syndrome
- Spectacles
- spectacle dispensing
- spectacle dispensing errors
- Indian eyes
- normative database
- retinal nerve fiber layer thickness
- spectral domain optical coherence tomography