Pelizaeus-Merzbacher Disease and Hypotonia

Abstract

Two brothers with Pelizaeus-Merzbacher disease presenting with neonatal hypotonia and hyporeflexia are reported from the Tuft’s University School of Medicine, and Massachusetts General Hospital, Boston, and the EKS Center for Mental Retardation, Waltham, MA.

Keywords

• pelizaeus-merzbacher disease
• severe hypotonia
• high-amplitude potentials