Mendelian randomization reveals causal effects of kidney function on various biochemical parameters

Sehoon Park; Soojin Lee; Yaerim Kim; Semin Cho; Hyeok Huh; Kwangsoo Kim; Yong Chul Kim; Seung Seok Han; Hajeong Lee; Jung Pyo Lee; Kwon Wook Joo; Chun Soo Lim; Yon Su Kim; Dong Ki Kim

doi:10.1038/s42003-022-03659-4

Communications Biology (Jul 2022)

Mendelian randomization reveals causal effects of kidney function on various biochemical parameters

Sehoon Park,
Soojin Lee,
Yaerim Kim,
Semin Cho,
Hyeok Huh,
Kwangsoo Kim,
Yong Chul Kim,
Seung Seok Han,
Hajeong Lee,
Jung Pyo Lee,
Kwon Wook Joo,
Chun Soo Lim,
Yon Su Kim,
Dong Ki Kim

Affiliations

Sehoon Park: Department of Biomedical Sciences, Seoul National University College of Medicine
Soojin Lee: Department of Internal Medicine, Uijeongbu Eulji University Medical Center
Yaerim Kim: Department of Internal Medicine, Keimyung University School of Medicine
Semin Cho: Department of Internal Medicine, Chung-Ang University Gwangmyeong Hospital
Hyeok Huh: Department of Internal Medicine, Inje University Busan Paik Hospital
Kwangsoo Kim: Transdisciplinary Department of Medicine & Advanced Technology, Seoul National University Hospital
Yong Chul Kim: Department of Internal Medicine, Seoul National University Hospital
Seung Seok Han: Department of Internal Medicine, Seoul National University Hospital
Hajeong Lee: Department of Internal Medicine, Seoul National University Hospital
Jung Pyo Lee: Department of Internal Medicine, Seoul National University College of Medicine
Kwon Wook Joo: Department of Internal Medicine, Seoul National University College of Medicine
Chun Soo Lim: Department of Internal Medicine, Seoul National University College of Medicine
Yon Su Kim: Department of Biomedical Sciences, Seoul National University College of Medicine
Dong Ki Kim: Department of Internal Medicine, Seoul National University College of Medicine

DOI: https://doi.org/10.1038/s42003-022-03659-4
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 8

Abstract

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Mendelian randomization analyses of estimated glomerular filtration rate (eGFR) in the UK Biobank cohort provide insight into the causal effects of kidney function on 60 biochemical parameters.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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