Chemoselective carbene insertion into the N−H bonds of NH3·H2O

Zhaohong Liu; Yong Yang; Qingmin Song; Linxuan Li; Giuseppe Zanoni; Shaopeng Liu; Meng Xiang; Edward A. Anderson; Xihe Bi

doi:10.1038/s41467-022-35394-z

Nature Communications (Dec 2022)

Chemoselective carbene insertion into the N−H bonds of NH3·H2O

Zhaohong Liu,
Yong Yang,
Qingmin Song,
Linxuan Li,
Giuseppe Zanoni,
Shaopeng Liu,
Meng Xiang,
Edward A. Anderson,
Xihe Bi

Affiliations

Zhaohong Liu: Department of Chemistry, Northeast Normal University
Yong Yang: Department of Chemistry, Northeast Normal University
Qingmin Song: Department of Chemistry, Northeast Normal University
Linxuan Li: Department of Chemistry, Northeast Normal University
Giuseppe Zanoni: Department of Chemistry, University of Pavia
Shaopeng Liu: Department of Chemistry, Northeast Normal University
Meng Xiang: Department of Chemistry, Northeast Normal University
Edward A. Anderson: Chemistry Research Laboratory, University of Oxford
Xihe Bi: Department of Chemistry, Northeast Normal University

DOI: https://doi.org/10.1038/s41467-022-35394-z
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 9

Abstract

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Converting low-cost inorganic chemicals into value-added organic chemicals is a longstanding goal in chemistry. Here the authors describe a silver-catalysed chemoselective carbene N−H insertion reaction, providing access to primary amines from aqueous ammonia and diazo compounds.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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