Comparison among information hiding methods in DNA Sequences

Abstract

By research, three methods for hiding secret message were proposed. In the first one the secret message was hid in a known DNA sequence belongs to prokaryotic organism Escherichia Coli k12 (E.Coli ) DNA sequence obtained from EBI location (European Bioinformatics Institute), Among the DNA molecule characters, one of the mutant ability types, that is the silent mutant, was chosen to hide a secret message within the sequence. The second method, a sequence of DNA has been synthesized chemically depending on the text secret message via using tables of symbols formed from English letter, numbers and special characters, each symbols represents codon and the symbols were arranged in the table in descending order depending on English letter frequency codon frequency (Genes). While in the third method the secret message was hid in E.Coli bacteria with known nitrogen base sequence in EBI using complementary character. The proposed methods applied in Matlab program and C# . Results of study revealed that DNA sequence has a high ratio for hiding secret message. The results reached 100% and the error rate to 0%.