Combined pharmacotherapy of arterial hypertension. Overview fixed combination antihypertensive drugs

Abstract

Hypertension remains the cornerstone of the cardiovascular continuum. An increasing number of patients receive a combination antihypertensive therapy to achieve target blood pressure, expanding indications for combination therapy at the onset of treatment. Constantly growing market of fixed combinations (FC) of antihypertensive drugs. The article gives an overview of the FC, registered in the Russian Federation, discussed the clinical situation for the preferential destination of a FC. A more detailed analysis of FC comprising the angiotensin II receptor blocker and diuretics, in particular, discusses the benefits of FC comprising angiotensin II receptor blocker candesartan and hydrochlorothiazide.

Keywords

• hypertension
• antihypertensive therapy
• rational pharmacotherapy
• combined pharmacotherapy
• a fixed combination
• thiazide diuretics
• hydrochlorothiazide
• angiotensin ii receptor blocker
• candesartan
• review