Indian Dermatology Online Journal (Jan 2016)

Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report

  • Aarti Salunke,
  • Vasudha Belgaumkar,
  • Ravindranath Chavan,
  • Rinkesh Dobariya

DOI
https://doi.org/10.4103/2229-5178.193913
Journal volume & issue
Vol. 7, no. 6
pp. 516 – 519

Abstract

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Progressive nodular histiocytosis (PNH) represents a very rare type of non-Langerhans cell histiocytosis. It is characterized by progressive appearance of papules and nodules without spontaneous resolution. We report a 60-year-old patient with novel clinical features in the form of extensive noduloulcerative lesions, ichthyotic patches, and laryngeal involvement culminating in fatal outcome prior to therapeutic intervention. Although the presenting features were baffling, histopathology and immunohistochemistry clinched the diagnosis of PNH.

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