OPPORTUNITIES FOR THE USE OF VISCERAL OBESITY INDEX IN METABOLIC SYNDROME DIAGNOSTICS AND PROGNOSIS OF ITS COMPLICATION RISK

Abstract

Aim. To study VAI as diagnostic marker for MS and its usefulness for prognosis of cardiovascular complications development in MS comparing to other common antropometric parameters (WR, BMI, WR/HR, WR/height, TG/HDL). Material and methods. Totally 301 person included (148 men, 153 women). All participants undewent anthropometry, BP measurement, fasting glucose, lipid profile, adiponectine. At second stage (follow-up) the participants were divided into two groups depending on end-points: first group had cardiovascular complications (CHD, MI, cardiovascular disease), second group — DM 2 type. MS was assessed with IDF (2005).Results. MS was found in 108 respondents (35,9%). Significant positive correlations were found between VI and BP, fasting glucose, LDL; negative — with VAI and adiponectine. Significant predictors for MS dignosis were WR/height, TG/HDL and VAI (p<0,0001). By the results of multiple regression VAI, WR/height and adiponectine were independent factors of cardiovascular risk in MS; and risk factors for DM 2 type were VAI, TG/HDL, adiponectine.Conclusion. VAI proved its diagnostic reliability in MS diagnostics, as in cardiovascular risk prognosis of MS. Further studies required with longer follow-up period and various patient groups.

Keywords

• visceral obesity index
• adiponectine
• metabolic syndrome