Solitary cellular neurofibroma of alveolar mucosa unassociated with neurofibromatosis-1

Abstract

Neurofibromas (NFs) are rare neurogenic tumors of the oral cavity. They can present as solitary, or multiple when associated with neurofibromatosis-1 (NF-1)/von Recklinghausen′s disease. Solitary intraoral NFs unassociated with NF-1 are sporadic and mimic any other soft tissue tumors of the oral cavity. Hence, final diagnosis can only be rendered after histopathological examination although they exhibit numerous microscopic variants. They show numerous mast cells and immunopositive for S-100 protein. Here, we are presenting one such case of NF in a 55-year-old male patient.

Keywords

• Alveolar mucosa, cellular neurofibroma, mast cells, neurofibromatosis-1, S-100, solitary neurofibroma