The Future Landscape and Framework of Precision Nutrition
Tianshu Han,
Wei Wei,
Wenbo Jiang,
Yiding Geng,
Zijie Liu,
Ruiming Yang,
Chenrun Jin,
Yating Lei,
Xinyi Sun,
Jiaxu Xu,
Juan Chen,
Changhao Sun
Affiliations
Tianshu Han
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China
Wei Wei
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China
Wenbo Jiang
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China
Yiding Geng
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China
Zijie Liu
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China
Ruiming Yang
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China
Chenrun Jin
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China
Yating Lei
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China
Xinyi Sun
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China
Jiaxu Xu
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China
Juan Chen
Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Corresponding authors.
Changhao Sun
Department of Nutrition and Food Hygiene, the National Key Discipline, School of Public Health, Harbin Medical University, Harbin 150081, China; Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, Harbin 150081, China; Corresponding authors.
The concept of precision nutrition was first proposed almost a decade ago. Current research in precision nutrition primarily focuses on comprehending individualized variations in response to dietary intake, with little attention being given to other crucial aspects of precision nutrition. Moreover, there is a dearth of comprehensive review studies that portray the landscape and framework of precision nutrition. This review commences by tracing the historical trajectory of nutritional science, with the aim of dissecting the challenges encountered in nutrition science within the new era of disease profiles. This review also deconstructs the field of precision nutrition into four key components: the proposal of the theory for individualized nutritional requirement phenotypes; the establishment of precise methods for measuring dietary intake and evaluating nutritional status; the creation of multidimensional nutritional intervention strategies that address the aspects of what, how, and when to eat; and the construction of a pathway for the translation and integration of scientific research into healthcare practices, utilizing artificial intelligence and information platforms. Incorporating these four components, this review further discusses prospective avenues that warrant exploration to achieve the objective of enhancing health through precision nutrition.
