Newer protocols and future in collagen cross-linking

Abstract

Corneal Cross-Linking (CXL) is an established surgical procedure for the treatment of corneal disorders such as corneal ectasia and keratoconus. This method of treatment stabilises the corneal structure and increases rigidity, reducing the requirement for corneal transplantation. Since its development, many scientific studies have been conducted to investigate ways of improving the procedure. Biomechanical stability of the cornea after exposure to UV-A light, and the effect of shortening procedure time has been some of the many topics explored

Keywords

• Epidemiology
• keratoconus
• prevalence
• Disease pathogenesis
• genetic heterogeneity
• genetics and genomics
• genome-wide association study
• genomic loci
• keratoconus
• linkage mapping
• molecular mechanisms
• whole exome-genome sequencing
• Deregulation
• ectasia
• gene expression
• keratoconus
• mass spectroscopy
• proteomics
• signaling pathways
• Cornea
• crosslinking
• keratoconus
• modulus
• Corneal topography
• imaging
• keratoconus
• optical coherence tomography
• placido disc based topography
• Ectatic disease
• keratoconus
• scheimpflug imaging
• Keratoconus
• ocular allergy
• vernal keratoconjunctivitis
• Contact lens
• keratoconus
• piggy back contact lenses
• rigid gas permeable
• scleral lens
• SynergEyes
• toric soft contact lens
• Corneal cross-linking techniques
• new technologies
• riboflavin
• Collagen cross linking
• Corneal collagen cross-linking
• hypoosmolar riboflavin
• keratoconus
• thin cornea
• transepithelial collagen cross-linking
• Corneal cross-linking
• radiant exposure
• ultraviolet-A