Biology and Life Sciences Forum (Nov 2023)

Mediterranean-like Diet May Modulate Acute Inflammation in Wistar Rats

  • Sergi Casanova-Crespo,
  • Daniela Ceballos-Sánchez,
  • María J. Rodríguez-Lagunas,
  • Malen Massot-Cladera,
  • Margarida Castell,
  • Francisco J. Pérez-Cano

DOI
https://doi.org/10.3390/IECN2023-15796
Journal volume & issue
Vol. 29, no. 1
p. 26

Abstract

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The Mediterranean diet (MD) is very rich in bioactive and immunomodulatory components. Some of these have demonstrated their protective activity in inflammation. The objective of this study was to evaluate the impact of a diet rich in fiber and polyphenols on an inflammatory process. The intervention was performed in two groups of 7-week-old rats, one receiving an experimental MD-like diet and another fed a reference diet (REF). At the end of the study, local inflammation was induced by injecting the rat’s paw with carrageenan. A lower paw volume was observed in = rats from the MD-like diet group.

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