Research Progress on Chiral Supramolecular Sensors for Enantiomer Detection
Xiao-Fan Wu,
Qing-Mei Ge,
Nan Jiang,
Wen-Feng Zhao,
Mao Liu,
Hang Cong,
Jiang-Lin Zhao
Affiliations
Xiao-Fan Wu
Collaborative Innovation Center of Guizhou Province for Efficient Utilization of Phosphorus and Fluorine Resources, Guizhou University, Guiyang 550025, China
Qing-Mei Ge
Collaborative Innovation Center of Guizhou Province for Efficient Utilization of Phosphorus and Fluorine Resources, Guizhou University, Guiyang 550025, China
Nan Jiang
Collaborative Innovation Center of Guizhou Province for Efficient Utilization of Phosphorus and Fluorine Resources, Guizhou University, Guiyang 550025, China
Wen-Feng Zhao
Collaborative Innovation Center of Guizhou Province for Efficient Utilization of Phosphorus and Fluorine Resources, Guizhou University, Guiyang 550025, China
Mao Liu
Collaborative Innovation Center of Guizhou Province for Efficient Utilization of Phosphorus and Fluorine Resources, Guizhou University, Guiyang 550025, China
Hang Cong
Collaborative Innovation Center of Guizhou Province for Efficient Utilization of Phosphorus and Fluorine Resources, Guizhou University, Guiyang 550025, China
Jiang-Lin Zhao
Precision Medicine R&D Center, Zhuhai Institute of Advanced Technology, Chinese Academy of Sciences, Zhuhai 519080, China
Chiral substances occur naturally in abiotic and living systems. The recognition and detection of chiral substances in the natural environment or their analysis and detection in biological systems are crucial. Chiral recognition is a research hotspot in clinical medicine, pharmacology, biochemistry, and other fields. Indeed, many researchers have developed various sensors with different functionalized materials for detecting and analyzing enantiomers. Supramolecular systems have important applications in the development of molecular recognition technologies, and the development of supramolecular chemistry is closely related to research on molecular devices. Therefore, this review summarizes the principle of chiral supramolecular sensors for the detection of enantiomers from the perspective of various sensor types, including optical, electrochemical, electrochemical luminescence, photoelectric, and supramolecular chemical sensors. This review also summarizes the relevant reports on chiral supramolecular sensors in the last five years. Finally, we highlight the prospects of supramolecular chiral sensors in future research.
