Stem Cell Research (Mar 2020)

Generation of a human control iPS cell line (ESi080‐A) from a donor with no rheumatic diseases

  • R. Castro-Viñuelas,
  • C. Sanjurjo-Rodríguez,
  • M. Piñeiro-Ramil,
  • S. Rodríguez-Fernández,
  • I.M. Fuentes-Boquete,
  • F.J. Blanco,
  • S.M. Díaz-Prado

Journal volume & issue
Vol. 43

Abstract

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Here, we report the establishment of the human iPS cell line N1-FiPS4F#7 generated from skin cells of a patient with no rheumatic diseases, thus obtaining an appropriate control iPS cell line for researchers working in the field of rheumatic diseases. The reprogramming factors Oct4, Sox2, Klf4 and c-Myc were introduced using a non-integrating reprogramming strategy involving Sendai Virus. Keywords: Human iPS, Reprogramming, Sendai virus, Pluripotency, Cell line, Embryoid body