Scientific Reports (Mar 2022)
Prevalence, awareness, treatment, and control of hypertension based on ACC/AHA versus JNC7 guidelines in the PERSIAN cohort study
- Sadaf Sepanlou,
- Farid Najafi,
- Hossein Poustchi,
- Mahboubeh Parsaeian,
- Ali Ahmadi,
- Mohammadhossein Somi,
- Farhad Moradpour,
- Reza Alizadeh-Navaei,
- Ali Gohari,
- Bijan Zamani,
- Ali Esmaeilinadimi,
- Abbas Rezaianzadeh,
- Fariborz Mansour-Ghanaei,
- Ehsan Bahramali,
- Alireza Ansari-Moghaddam,
- Behrooz Hamzeh,
- Elham Zanganeh Yousefabadi,
- Mohammad Javad Zare Sakhvidi,
- Iraj Mohebbi,
- Mohammad Reza Fattahi,
- Azim Nejatizadeh,
- Hossein Marioryad,
- Nazgol Motamed-Gorji,
- Farzin Roozafzai,
- Sareh Eghtesad,
- Zahra Mohammadi,
- Amaneh Shayanrad,
- Maryam Sharafkhah,
- Arash Etemadi,
- Farin Kamangar,
- Stephen P. Juraschek,
- Reza Malekzadeh
Affiliations
- Sadaf Sepanlou
- Digestive Disease Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences
- Farid Najafi
- Research Center for Environmental Determinants of Health, Health Institute, Kermanshah University of Medical Sciences
- Hossein Poustchi
- Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences
- Mahboubeh Parsaeian
- Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences
- Ali Ahmadi
- Department of Epidemiology and Biostatistics, Modeling in Health Research Center, School of Health, Shahrekord University of Medical Sciences
- Mohammadhossein Somi
- Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences
- Farhad Moradpour
- Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences
- Reza Alizadeh-Navaei
- Gastrointestinal Cancer Research Center, Non-Communicable Diseases Institute, Mazandaran University of Medical Sciences
- Ali Gohari
- Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences
- Bijan Zamani
- Digestive Disease Research Center, Ardabil University of Medical Sciences
- Ali Esmaeilinadimi
- Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences
- Abbas Rezaianzadeh
- Colorectal Research Center, Shiraz University of Medical Sciences
- Fariborz Mansour-Ghanaei
- Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences
- Ehsan Bahramali
- Noncommunicable Diseases Research Center, Fasa University of Medical Sciences
- Alireza Ansari-Moghaddam
- Health Promotion Research Center, Zahedan University of Medical Sciences
- Behrooz Hamzeh
- Research Center for Environmental Determinants of Health, Health Institute, Kermanshah University of Medical Sciences
- Elham Zanganeh Yousefabadi
- Department of Internal Medicine, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences
- Mohammad Javad Zare Sakhvidi
- Occupational Health Research Centre, School of Public Health, Shahid Sadoughi University of Medical Sciences
- Iraj Mohebbi
- Social Determinants of Health Research Center, Clinical Research Institute, Urmia University of Medical Sciences
- Mohammad Reza Fattahi
- Gastroenterohepatology Research Center, Shiraz University of Medical Sciences
- Azim Nejatizadeh
- Molecular Medicine Research Center, Hormozgan University of Medical Sciences
- Hossein Marioryad
- Yasuj University of Medical Sciences
- Nazgol Motamed-Gorji
- Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences
- Farzin Roozafzai
- Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences
- Sareh Eghtesad
- Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences
- Zahra Mohammadi
- Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences
- Amaneh Shayanrad
- Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences
- Maryam Sharafkhah
- Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences
- Arash Etemadi
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- Farin Kamangar
- Department of Biology, School of Computer, Mathematical, and Natural Sciences, Morgan State University
- Stephen P. Juraschek
- Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School
- Reza Malekzadeh
- Digestive Oncology Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences
- DOI
- https://doi.org/10.1038/s41598-022-07896-9
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 10
Abstract
Abstract In this cross-sectional population-based study, we used the baseline data of the Prospective Epidemiologic Research Studies in IrAN cohort study collected in Iran from 2014 to 2020. The main outcomes were the prevalence of hypertension and proportion of awareness, treatment, and control based on the 2017 ACC/AHA guideline compared to the seventh report of the Joint National Committee (JNC7). Of the total of 163,770 participants, aged 35–70 years, 55.2% were female. The sex-age standardized prevalence of hypertension was 22.3% (95% CI 20.6, 24.1) based on the JNC7 guideline and 36.5% (31.1, 41.8) based on the ACC/AHA guideline. A total of 24,312 participants [14.1% (10.1, 18.1)] were newly diagnosed based on the ACC/AHA guideline. Compared to adults diagnosed with hypertension based on the JNC7 guideline, the newly diagnosed participants were mainly young literate males who had low levels of risk factors and were free from conventional comorbidities of hypertension. About 30.7% (25.9, 35.4) of them (4.3% of the entire population) were eligible for pharmacologic intervention based on the ACC/AHA guideline. Implementation of the new guideline may impose additional burden on health systems. However, early detection and management of elevated blood pressure may reduce the ultimate burden of hypertension in Iran.
