Nature Communications (Jul 2019)

Transposition favors the generation of large effect mutations that may facilitate rapid adaption

  • Leandro Quadrana,
  • Mathilde Etcheverry,
  • Arthur Gilly,
  • Erwann Caillieux,
  • Mohammed-Amin Madoui,
  • Julie Guy,
  • Amanda Bortolini Silveira,
  • Stefan Engelen,
  • Victoire Baillet,
  • Patrick Wincker,
  • Jean-Marc Aury,
  • Vincent Colot

DOI
https://doi.org/10.1038/s41467-019-11385-5
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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The contribution of transposable elements (TEs) to the creation of heritable mutations is unknown. Here the authors show in Arabidopsis that TEs accumulate exponentially once mobilized and that COPIA retrotransposons preferentially integrate in environmental response genes in a H2A.Z-dependent manner.