3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione

Plamen Angelov; Paraskeva Terziyska; Danail Georgiev

doi:10.3390/M1556

Molbank (Jan 2023)

3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione

Plamen Angelov,
Paraskeva Terziyska,
Danail Georgiev

Affiliations

Plamen Angelov: Department of Organic Chemistry, University of Plovdiv Paisii Hilendarski, 24 Tsar Asen Str., 4000 Plovdiv, Bulgaria
Paraskeva Terziyska: Department of Organic Chemistry, University of Plovdiv Paisii Hilendarski, 24 Tsar Asen Str., 4000 Plovdiv, Bulgaria
Danail Georgiev: Department of Biochemistry and Microbiology, University of Plovdiv Paisii Hilendarski, 24 Tsar Asen Str., 4000 Plovdiv, Bulgaria

DOI: https://doi.org/10.3390/M1556
Journal volume & issue: Vol. 2023, no. 1
p. M1556

Abstract

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3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione was obtained as an unexpected product in a three-step synthesis starting with o-nitrobenzoyl sarcosine, acetoacetanilide and ethylamine. The compound showed moderate antibacterial activity against S. aureus and E. coli.

Published in Molbank

ISSN: 1422-8599 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Inorganic chemistry
Website: https://www.mdpi.com/journal/molbank

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