INVESTIGATION OF NEUROPROTECTIVE ACTIVITY THIOPHANE INVOLUTIONAL CHORIORETINAL DEGENERATION IN RATS OXYS

Abstract

The method of spontaneous and induced luminol -dependent chemiluminescence in homogenates of rat retinas OXYS registered increase in the generation of free radicals against decrease in total antioxidant activity. With the ultra-microscopic and quantitative analysis revealed degenerative retinal neurons rats OXYS: the percentage increase in neurosensory cells with pyknosis of nuclei, hyperchromatic piknomorfnyh associative neurons and ganglion n eurons that have been modified on a light and dark type. Thiophane, limiting free radical reactions in the retina and protects retinal neurons from damage.

Keywords

• морфология сетчатки
• центральная хориоретинальная дегенерация
• крысы oxys
• антиоксидантная активность
• свободные радикалы
• люминол-зависимая хемилюминесценция
• тиофан