Epidemiological Rationale for Changing the Strategy and Tactics of Vaccination of Pertussis in Current Conditions

Abstract

A research objective – definition of the main directions of improvement of epidemiological control of a pertussis on the basis of studying of manifestations of epidemic process and its determinants. Materials and methods. The analysis of incidence is carried out according to official statistics in 19 years, the population antipertussoid immunity is studied by results of routine serological monitoring and specially organized screening researches. At discussion of results and development of recommendations WHO recommendations and the published articles of domestic and foreign authors are used. Results. Activation of epidemic process of pertussis in modern conditions in all age groups of the population is revealed. Risk factors of incidence of children about one year and the main sources of their infection, low level of a seroprotektion at children of 3–4 years old, the hidden circulation of Bordetella pertussis in group of children of 6-7 years, high susceptibility to whooping cough of adult population, including pregnant women are established. Conclusion. The directions of optimization of vaccinal prevention of pertussis are defined: strengthening of supervising functions behind completeness and timeliness of immunization of children of the first year of life; wider use for immunization of children from risk groups of the combined vaccines containing an acellular component; to enter into the National schedule according to epidemic indications a revaccination against pertussis of children of of 6–7 years and adults from groups of epidemiological and social risk with the subsequent step-by-step introduction of a revaccination of teenagers and adult each 10 years along with diphtheritic and tetanic anatoxins.

Keywords

• pertussis
• incidence
• tactics of immunization