Important Flavonoids and Their Role as a Therapeutic Agent
Asad Ullah,
Sidra Munir,
Syed Lal Badshah,
Noreen Khan,
Lubna Ghani,
Benjamin Gabriel Poulson,
Abdul-Hamid Emwas,
Mariusz Jaremko
Affiliations
Asad Ullah
Department of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan
Sidra Munir
Department of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan
Syed Lal Badshah
Department of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan
Noreen Khan
Department of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan
Lubna Ghani
Department of Chemistry, The University of Azad Jammu and Kashmir, Muzaffarabad, Azad Kashmir 13230, Pakistan
Benjamin Gabriel Poulson
Division of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia
Abdul-Hamid Emwas
Core Labs, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia
Mariusz Jaremko
Division of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia
Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of medicinal benefits, including anticancer, antioxidant, anti-inflammatory, and antiviral properties. They also have neuroprotective and cardio-protective effects. These biological activities depend upon the type of flavonoid, its (possible) mode of action, and its bioavailability. These cost-effective medicinal components have significant biological activities, and their effectiveness has been proved for a variety of diseases. The most recent work is focused on their isolation, synthesis of their analogs, and their effects on human health using a variety of techniques and animal models. Thousands of flavonoids have been successfully isolated, and this number increases steadily. We have therefore made an effort to summarize the isolated flavonoids with useful activities in order to gain a better understanding of their effects on human health.