Features of post-COVID syndrome in patients who had COVID-19: effects on the cardiovascular system

Abstract

Summary. At the beginning of the pandemic, COVID-19 was thought to be a short-lived disease. However, in the summer of 2020, the World Health Organization, using available data at the time, reported that some patients had symptoms of exhaustion for weeks or even months. Clinical studies of patients infected with SARS-CoV-2 have shown damage to many organs or systems, including the lungs, brain, kidneys and cardiovascular system. Despite extensive research into the cardiovascular complications of COVID-19 and its mechanisms, a number of unanswered questions remain unresolved. However, it is worth noting, that the study should also identify the target group, terms of screening after initial recovery from COVID-19 and tests, which will help in sorting people, who are at risk. The aim of the study – to analyze modern literature sources on post-COVID syndrome in patients with comorbid COVID-19 and cardiovascular pathology. Materials and Methods. The study examined the scientific publications of recent years, which are available on the Internet, key words "COVID-19", "SARS-CoV-2", key words "COVID-19","SARS-CoV-2", "post-COVID syndrome", "cardiovascular pathology". Results. The presence of cardiovascular disease increases mortality in patients with COVID-19 and cardiovascular damage, including myocarditis, cardiac arrhythmias, endothelial cell lesions, thrombotic events and interstitial myocardial fibrosis, postural orthostatic tachycardia syndrome, observed in individual patients who underwent COVID-19. The main pathophysiology of cardiovascular complications associated with COVID-19, not fully studied, although direct myocardial viral infection and cytokine storm have been suggested as possible mechanisms. Conclusions. The analysis of literature sources substantiates the relevance of the study of post-COVID syndrome in patients with comorbid course of COVID-19 and cardiovascular disease. Defining the role of COVID-19 in the development and progression of cardiovascular disease will pave the way for new approaches to the diagnosis, stratification, monitoring, prevention and treatment of this disease

Keywords

• covid-19
• post-covid syndrome
• cardiovascular pathology