Urology Case Reports (Jan 2025)

Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old male

  • Austin G. Kazarian,
  • Caleb Q. Ashbrook,
  • Charles F. Timmons,
  • Craig A. Peters,
  • Bruce J. Schlomer

Journal volume & issue
Vol. 58
p. 102884

Abstract

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Sertoli cell tumors are a rare type of sex-cord stromal tumor. We present a case of a thirteen-year-old male presenting with 2–3 months of fevers and twenty-pound weight loss. Evaluation revealed leukocytosis, anemia, elevated systemic inflammatory markers and a negative infectious disease evaluation. An evaluation for malignancy revealed an incidental testicular mass. A radical orchiectomy lead to prompt resolution of fevers, leukocytosis, and elevated systemic inflammatory markers. Final pathology was consistent with a Sertoli cell tumor. To our knowledge, this is the first reported case of a Sertoli cell tumor presenting with fever, leukocytosis, and weight loss.

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