Secondary prevention effectiveness in patients with stable angina

Abstract

Aim. To assess the effectiveness of pharmaceutical secondary prevention in ambulatory patients with stable angina (SA), in the real-worl clinical settings. Material and methods. Retrospective analysis of randomly selected ambulatory medical histories (n=1067; year 2006) of SA patients attending Bishkek centres of family medicine. Results. The main groups of anti-anginal medications (AAM), prescribed by primary healthcare doctors, were beta-adrenoblockers (BAB; 43,0 %), nitrates (28,6 %), and calcium antagonists (CA; 27,9 %). Anti-aggregants were prescirbed to 86,8 % of the patients, and ACE inhibitors — to 82,2 %. Myocardial cytoprotectors were prescribed less often (0,5 %), as well as lipid-lowering agents (8,4 %). The prescribed doses of lipid-lowering agents were inadequately low (minimal effective doses). Generic lipid-lowering medications were prescrbed more often (93,3 %) than the original ones (6,7 %). Conclusion. Pharmaceutical secondary prevention in SA patients was not adequate and did not comply with the modern clinical guidelines.

Keywords

• стабильная стенокардия
• фармакотерапия
• вторичная профилактика