IMMUNOLOGICAL AND PATHOPHYSIOLOGICAL MECHANISMS OF SYSTEMIC INFLAMMATION

Abstract

Abstract. The lecture presents modern data on systemic inflammation, as well as an original concept of its genesis. This disorder is considered a typical pathological process being fundamental to pathogenesis of the most critical states of different origin. Distinct features of “classical” and systemic inflammation are discussed, whereas the underlying immunological and pathophysiological mechanisms of inflammation are subject to classification. Main constitutive processes, phases of systemic inflammation, and certain variants of their proceeding are characterized as well. A definition of “systemic alteration” has been specified.

Keywords

• systemic inflammation
• typical pathological process