PLoS ONE (Jan 2011)

MR angiography of collateral arteries in a hind limb ischemia model: comparison between blood pool agent Gadomer and small contrast agent Gd-DTPA.

  • Karolien Jaspers,
  • Bas Versluis,
  • Tim Leiner,
  • Petra Dijkstra,
  • Marlies Oostendorp,
  • Jolanda M van Golde,
  • Mark J Post,
  • Walter H Backes

DOI
https://doi.org/10.1371/journal.pone.0016159
Journal volume & issue
Vol. 6, no. 1
p. e16159

Abstract

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The objective of this study was to compare the blood pool agent Gadomer with a small contrast agent for the visualization of ultra-small, collateral arteries (diameter0.10). Inter-observer variation was 24% and 18% for Gadomer and Gd-DTPA, respectively. In conclusion, blood pool agent Gadomer improved vessel conspicuity compared to Gd-DTPA. Steady-state MRA can be considered as an excellent non-invasive alternative to intra-arterial XRA for the visualization of ultra-small collateral arteries.