Review and Thinking on Forensic Pathological Changes of Coronavirus-Infected Diseases
ZHOU Nan,
ZHAO Qian-hao,
ZHENG Jing-jing,
MAO Dan-mi,
ZHENG Da,
HU Bing-jie,
CHENG Jian-ding
Affiliations
ZHOU Nan
Guangdong Province Translational Forensic Medicine Engineering Technology Research Center, Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
ZHAO Qian-hao
Guangdong Province Translational Forensic Medicine Engineering Technology Research Center, Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
ZHENG Jing-jing
Guangdong Province Translational Forensic Medicine Engineering Technology Research Center, Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
MAO Dan-mi
Guangdong Province Translational Forensic Medicine Engineering Technology Research Center, Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
ZHENG Da
Guangdong Province Translational Forensic Medicine Engineering Technology Research Center, Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
HU Bing-jie
Department of Pathology, Guangdong Medical University, Guangzhou 511436, China
CHENG Jian-ding
Guangdong Province Translational Forensic Medicine Engineering Technology Research Center, Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
Since the beginning of this century, three types of coronavirus have widely transmitted and caused severe diseases and deaths, which strongly indicates that severe infectious diseases caused by coronavirus infection are not accidental events. Coronavirus-infected diseases are mainly manifested by respiratory symptoms, with multiple organ dysfunctions. Precisely investigating the pathological process, characteristics and pathogenesis of coronavirus-infected diseases will be beneficial for us to understand clinical manifestations and provide targeted suggestions on prophylaxis and treatment. This paper briefly reviews the pathological findings of three known coronavirus-infected diseases, and attempts to construct the pathological spectrum of coronavirus-infected diseases, aiming to provide reference and thinking for autopsy, histopathological examination and animal infection model study of coronavirus-infected diseases.
