The Association between Adverse Events in the Last 5 Years and the Rate of Breast Cancer

Abstract

Background: This study was conducted in Yazd Province, Central Iran aimed to investigate the relationship between adverse events and breast cancer during 2012-2014. Methods: Hospital-based case-control study of 150 women with breast cancer and 150 healthy women (did not have breast cancer) was conducted. Sampling was performed in the form of accessibility. Data collection was conducted using questionnaire through interview. The collected data were entered into SPSS for statistical analysis. Results: The mean age of participants was 51.58 yr. Eight percent of cases and 1.3% of the controls had experienced the sister’s death over the past 5 yr, this difference was statistically significant (P=0.03). Factors such as disability due to illness, divorce, unemployment, the second marriage, addiction, ill spouse, child’s problems (such as conflict, unemployment, addiction, legal troubles, illness), taking care of their own parents or their husband’s parents, migration, change of habitat, loss of home, communication problems, job-relevant factors were not significantly different between the two groups (P>0.05). Mean of severity of adverse events in both groups was significantly different (8.92±8.29 in the case group, 5.72±5.6 in the control group) (P=0.000). Conclusion: There was no significant relationship between adverse events in the last 5 yr and the risk of breast cancer. Factors such as personality and ability to cope with problems may positively influence this relationship.

Keywords

• Breast cancer
• Adverse events
• Case-control
• Iran