AIP Advances (Mar 2013)

Single cell in-vivo carbon nanotube device with multimodal sensing potential

  • Alexandra Scavelli,
  • Abhishek Gottipati,
  • Everett Comfort,
  • Sabarinath Jayaseelan,
  • Thomas Murray,
  • Michael Rizzolo,
  • Scott Tenenbaum,
  • Ji Ung Lee

DOI
https://doi.org/10.1063/1.4795408
Journal volume & issue
Vol. 3, no. 3
pp. 032122 – 032122

Abstract

Read online

Single walled carbon nanotube (SWNT) field effect transistors (NTFETs) are quickly becoming the foundation for bioelectronic sensors. We describe a multimodal NTFET device that could be used as a real time single cell biosensor with the potential for chemical, optical and electrical sensing capabilities. This device utilizes the natural movement of a cell through the trench of a NTFET to provide a working cell-SWNT interaction where the nanotube is suspended. The use of individual suspended SWNTs in lieu of non-suspended SWNTs in our device provides the basis for an in vivo NTFET multimodal single cell biosensor.