Revista da Sociedade Brasileira de Medicina Tropical (Mar 2021)

Treatment of tegumentary leishmaniasis in two hemodialysis patients with end-stage renal disease using two series of pentamidine

  • Karla Cristina Petruccelli,
  • Kátia Nascimento Couceiro,
  • Maria das Graças Vale Barbosa Guerra,
  • Zanair Soares Vasconcelos,
  • Alba Regina Jorge Brandão,
  • Monica Hosannah Silva e Silva,
  • Jorge Augusto de Oliveira Guerra

DOI
https://doi.org/10.1590/0037-8682-0633-2020
Journal volume & issue
Vol. 54

Abstract

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Abstract In this study, we present two cases of cutaneous leishmaniasis in patients with end-stage renal disease, who were treated solely with intramuscular pentamidine. In such cases, treatment implies a fine line between therapeutic efficacy and toxicity. This is suggestive of a knowledge gap; however, findings indicate that this is still the fastest and safest alternative to the treatment with antimonials. Also, it can help avoid the side effects that occur upon using antimonials.

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