Feasibility and Safety of Transjugular Liver Biopsy for Japanese Patients with Chronic Liver Diseases

Makoto Iijima; Takahiro Arisaka; Akira Yamamiya; Keiichi Tominaga; Kazunori Nagashima; Akira Kanamori; Satoshi Masuyama; Yuichi Majima; Kenichi Goda; Kazuyuki Ishida; Atsushi Irisawa

doi:10.3390/diagnostics11010131

Diagnostics (Jan 2021)

Feasibility and Safety of Transjugular Liver Biopsy for Japanese Patients with Chronic Liver Diseases

Makoto Iijima,
Takahiro Arisaka,
Akira Yamamiya,
Keiichi Tominaga,
Kazunori Nagashima,
Akira Kanamori,
Satoshi Masuyama,
Yuichi Majima,
Kenichi Goda,
Kazuyuki Ishida,
Atsushi Irisawa

Affiliations

Makoto Iijima: Department of Gastroenterology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan
Takahiro Arisaka: Department of Gastroenterology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan
Akira Yamamiya: Department of Gastroenterology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan
Keiichi Tominaga: Department of Gastroenterology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan
Kazunori Nagashima: Department of Gastroenterology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan
Akira Kanamori: Department of Gastroenterology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan
Satoshi Masuyama: Department of Gastroenterology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan
Yuichi Majima: Department of Gastroenterology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan
Kenichi Goda: Department of Gastroenterology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan
Kazuyuki Ishida: Department of Diagnostics Pathology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan
Atsushi Irisawa: Department of Gastroenterology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan

DOI: https://doi.org/10.3390/diagnostics11010131
Journal volume & issue: Vol. 11, no. 1
p. 131

Abstract

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Background and study aim: Transjugular liver biopsy (TJLB) can be used in patients who are ineligible for percutaneous liver biopsy (PLB) with acute and chronic hepatic disease. This study aimed to evaluate the usefulness and safety of TJLB in patients who were not indicated for PLB. Methods: Between July 2014 and February 2019, a total of 134 patients underwent liver biopsies at our institution. Among these, PLB was performed in 110 patients and TJLB in 24 patients. A retrospective comparison of clinical results in these patients was then performed. The primary endpoints of this study were the utility and safety of TJLB in patients who were not indicated for PLB. Results: The procedural success rate was 100% in both groups. The clinical response rate and the effective tissue sampling rate were 100% in the TJLB group and 97% in the PLB group (p = 0.55). There was no difference in the number of portal fields examined retrospectively between the two groups. No serious adverse events were observed in either group. Conclusions: It is suggested that TJLB is useful because it can be safely performed in patients with poor general condition who are not indicated for PLB.

Published in Diagnostics

ISSN: 2075-4418 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: http://www.mdpi.com/journal/diagnostics

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