Nature Communications (Jun 2018)

Out-of-equilibrium microcompartments for the bottom-up integration of metabolic functions

  • Thomas Beneyton,
  • Dorothee Krafft,
  • Claudia Bednarz,
  • Christin Kleineberg,
  • Christian Woelfer,
  • Ivan Ivanov,
  • Tanja Vidaković-Koch,
  • Kai Sundmacher,
  • Jean-Christophe Baret

DOI
https://doi.org/10.1038/s41467-018-04825-1
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Generating artificial cells able to carry out metabolic activities out-of-equilibrium is a current challenge in synthetic biology. Here the authors use a microfluidic platform for integration and analysis of minimal metabolic reactions in artificial microcompartments formed of water-in-oil droplets.