World Journal of Nuclear Medicine (Apr 2017)

Liver metastasis of lung cancer detected with similar uptake pattern on bone scintigraphy and fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography: What's the pathophysiologic mechanism?

  • Funda Üstün,
  • Salim Aksoy,
  • Burcu Serim,
  • Gülay Altun

DOI
https://doi.org/10.4103/1450-1147.203069
Journal volume & issue
Vol. 16, no. 02
pp. 163 – 165

Abstract

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Bone scintigraphy with 99mTc diphosphonates may exhibit extraosseous lesions in addition to metastatic lesions. Multiple factors can affect extraosseous 99mTc methylene diphosphonate (MDP) uptake. Similar uptake pattern of 99mTc MDP and fluorine-18 fluorodeoxyglucose (18F FDG) in hepatic metastasis was not already notified. In our case, initial tumor necrosis and subsequent intracellular calcification resulted in similar 99mTc MDP and 18F FDG accumulation in the metastatic area.

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