Nature Communications (Mar 2021)
The amyloid structure of mouse RIPK3 (receptor interacting protein kinase 3) in cell necroptosis
Abstract
Receptor Interacting Protein Kinase 3 (RIPK3) has a key role in TNF-induced necroptosis. Here, the authors combine solid state NMR measurements, MD simulations and cell based assays to characterize mouse RIPK3 and they present the structure of the RIPK3 amyloid core.