Second primary squamous cell carcinoma of nasal cavity after successful curative radiotherapy and chemotherapy of cancer of the cavum (UCNT)

Abstract

After nasopharyngeal carcinoma treatment, secondary malignant tumors of the nasal cavities in the irradiated zone are extremely rare, with an estimated frequency of 0.15%-0.75%. They are more common in young persons who do not have traditional risk factors. The clinical symptomatology is dominated by nasal obstruction. The major goal of the CT-MRI imaging workup is to figure out the optimal treatment plan. However, histological confirmation of the diagnosis is required. The purpose of this case report is to explain the radiological characteristics of squamous cell carcinoma as seen on MRI, as well as to examine the literature on the carcinogenic risk of radiotherapy and chemotherapy.

Keywords

• Second primary squamous cell carcinoma
• Radiotherapy
• Chemotherapy
• Nasal cavity