Drosophila hedgehog signaling range and robustness depend on direct and sustained heparan sulfate interactions

• Dominique Manikowski,
• Georg Steffes,
• Jurij Froese,
• Sebastian Exner,
• Kristina Ehring,
• Fabian Gude,
• Daniele Di Iorio,
• Seraphine V. Wegner,
• Kay Grobe

Affiliations

Dominique Manikowski

Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany

Georg Steffes

Institute of Neuro- and Behavioral Biology, University of Münster, Münster, Germany

Jurij Froese

Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany

Sebastian Exner

Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany

Kristina Ehring

Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany

Fabian Gude

Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany

Daniele Di Iorio

Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany

Seraphine V. Wegner

Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany

Kay Grobe

Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany